CAS NO. |
604-32-0 |
|
EINECS NO. |
210-064-3 |
FORMULA |
C34H50O2 |
MOL WT. |
490.77 |
H.S. CODE
|
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TOXICITY
|
|
DERIVATION |
|
CLASSIFICATION
|
|
SYNONYMS |
Cholest-5-en-3-ol
benzoate |
Cholest-5-ene-3-beta-yl benzoate Benzoato de colest-5-eno-3-á -ilo Benzoate de cholest-5-è ne-3-beta-yle |
PHYSICAL AND CHEMICAL PROPERTIES
|
PHYSICAL STATE |
white powder |
MELTING POINT |
148 - 150 C |
BOILING POINT |
|
SPECIFIC GRAVITY |
|
SOLUBILITY IN WATER |
Insoluble |
pH |
|
VAPOR DENSITY |
|
AUTOIGNITION
|
|
NFPA RATINGS
|
Health: 1 Flammability: 0 Reactivity: 0 |
REFRACTIVE INDEX
|
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FLASH POINT |
|
STABILITY |
Stable under ordinary conditions. |
GENERAL DESCRIPTION & APPLICATIONS
|
Cholesterol is a steroid alcohol that is essentially insoluble in aqueous
solutions. In mammals, it is normally solubilized by its association with other
lipids, such as phospholipids or bile acids thus, most cholesterol is found in
cell membranes, plasma lipoproteins, and bile. Cholesterol can be esterified
with a fatty acid to form cholesteryl esters. The latter form discrete lipid
droplets in cells, especially in cells of steroidogenic tissues, and in the
lipid core of low-density lipoproteins in the blood. Cholesterol is a fatty lipid
sparingly insoluble in water but soluble in a number of organic solvents. It is
the most common sterol of eukaryotes which a key constituent of cell membranes
and works as the precursor of bile acids, cholecalciferol (vitamin D) and
steroid hormones including cortisol, cortisone, aldosterone and sex hormone
progesterone in vertebrates. Cholesterol is used as an emulsifying agent in pharmaceuticals. The most cholesterols are synthesized by the liver and other tissues include the
adrenal glands and reproductive organs. Some cholesterol is absorbed from
dietary sources. The largest concentration of cholesterol is in the myelin
sheath that surrounds nerves and in the plasma membrane that surrounds all cells
in vertebrates (25% of brain lipid is cholesterol). Cholesterol can be esterified with a fatty acid to form
cholesteryl esters which form discrete lipid droplets in cells, especially in
cells of steroidogenic tissues, and in the lipid core of low-density
lipoproteins in the blood. The collection on the walls of arteries interferes
with the flow of blood. The High level of cholesterol in the blood is a major
risk factor for coronary heart diseases. Cholesteric materials are liquid crystals of mesomorphic phase in which molecules are parallel to each other within the plane of a layer, but the direction is oriented in loose parallel lines to form a helix through the layers. Cholesteric materials are temperature sensitive and have color changing ability upon temperature. Not only emulsifying and humectant properties but also liquid crystal properties of cholesterol and its derivatives (salts and esters) make them useful in the commercial applications of cosmetics and pharmaceuticals. |
SALES SPECIFICATION |
APPEARANCE
|
white powder |
ASSAY
|
97.5% min
|
LOSS ON DRYING
|
1.0% max
|
OPTICAL ROTATION
|
-13° ~ -17°
|
MELTING
POINT |
148 - 150 C |
TRANSPORTATION |
PACKING |
|
HAZARD CLASS |
|
UN NO. |
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OTHER INFORMATION |
Hazard Symbols: , Risk Phrases: , Safety Phrases: 22-24/25 |
CAS # OF CHOLESTERYL COMPOUNDS |
- CHOLESTERYL ACETOACETATE
- CHOLESTERYL ACETATE (CAS RN: 604-35-3)
- CHOLESTERYL ARACHIDONATE (CAS RN: 604-34-2)
- CHOLESTERYL BEHENATE (CAS RN: 61510-09-6)
- CHOLESTERYL BENZOATE (CAS RN: 604-32-0)
- CHOLESTERYL BROMIDE (CAS RN: 516-91-6)
- CHOLESTERYL BUTOXYPHENYLCARBONATE
- CHOLESTERYL BUTYL ETHER (CAS RN: 10322-03-9)
- CHOLESTERYL TERT-BUTYL ETHER
- CHOLESTERYL BUTYRATE (CAS RN: 521-13-1)
- CHOLESTERYL CAPRATE (CAS RN: 1183-04-6)
- CHOLESTERYL CAPROATE (CAS RN: 1062-96-0)
- CHOLESTERYL CAPRYLATE (CAS RN: 1182-42-9)
- CHOLESTERYL CHLORIDE (CAS RN: 910-31-6)
- CHOLESTERYL-P-CHLOROBENZOATE
- CHOLESTERYL CHLOROFORMATE (CAS RN: 7144-08-3)
- CHOLESTERYL-P-CHLOROPHENYLACETATE
- CHOLESTERYL-3-CHLOROPROPIONATE
- CHOLESTERYL CINNAMATE (CAS RN: 1990-11-0)
- CHOLESTERYL COUMARIN-3-CARBOXYLATE (CAS RN: 196091-78-8)
- CHOLESTERYL CROTONATE
- CHOLESTERYL DECYLATE
- CHOLESTERYL CROTYLCARBONATE (CAS RN: 62637-94-9)
- CHOLESTERYL-2,4-DICHLOROBENZOATE (CAS RN: 32832-01-2)
- CHOLESTERYL-3,4-DICHLOROBENZOATE (CAS RN: 32834-71-2)
- CHOLESTERYL 3BETA-N-(DI METHYL AMINO ETHYL) CARBAMATE HYDROCHLORIDE (CAS RN: 166023-21-8)
- CHOLESTERYL-3,5-DINITROBENZOATE (CAS RN: 25279-63-4)
- CHOLESTERYL ELAIDATE (CAS RN: 19485-76-8)
- CHOLESTERYL ERUCATE (CAS RN: 24516-39-0)
- CHOLESTERYL ETHYL ETHER (CAS RN: 986-19-6)
- CHOLESTERYL ETHYL CARBONATE
- CHOLESTERYL-2-(ETHOXYETHOXY)ETHYL CARBONATE (CAS RN: 15484-00-1)
- CHOLESTERYL-2-ETHYLHEXANOATE (CAS RN: 41329-01-5)
- CHOLESTERYL-2-ETHYLHEXYLCARBONATE
- CHOLESTERYL FORMATE (CAS RN: 4351-55-7)
- CHOLESTERYL-BETA-D-GLUCOSIDE
- CHOLESTERYL HEMISUCCINATE (CAS RN: 1510-21-0)
- CHOLESTERYL HEMISUCCINATE TRIS SALT (CAS RN: 102601-49-0)
- CHOLESTERYL HEPTADECANOATE (CAS RN: 24365-37-5)
- CHOLESTERYL HEPTYLATE (CAS RN: 1182-07-6)
- CHOLESTERYL HYDROGEN PHTHALATE
- CHOLESTERYL IODIDE
- CHOLESTERYL ISOAMYL ETHER
- CHOLESTERYL ISOBUTYRATE (CAS RN: 1180-43--4)
- CHOLESTERYL ISOPROPYL ETHER (CAS RN: 1255-86--3)
- CHOLESTERYL ISOSTEARYL CARBONATE (CAS RN: 127512-93-0)
- CHOLESTERYL ISOTRIDECYLCARBONATE
- CHOLESTERYL ISOVALERATE
- CHOLESTERYL LAURATE (CAS RN: 1908-11-8)
- CHOLESTERYL LINOLEATE (CAS RN: 604-33-1)
- CHOLESTERYL LINOLENATE (CAS RN: 2545-22-4)
- CHOLESTERYL METHYL CARBONATE (CAS RN: 15507-52--5)
- O-CHOLESTERYL S-METHYL DITHIOCARBONATE
- CHOLESTERYL METHYL ETHER (CAS RN: 1174-92-1)
- CHOLESTERYL METHYL SUCCINATE
- CHOLESTERYL MYRISTATE (CAS RN: 1989-52-2)
- CHOLESTERYL NERVONATE (CAS RN: 60758-73-8)
- CHOLESTERYL NITRATE
- CHOLESTERYL-P-NITROBENZOATE (CAS RN: 23838-12-2)
- CHOLESTERYL-P-NONYLPHENYL CARBONATE (CAS RN: 60474-62-6)
- CHOLESTERYL OLEATE (CAS RN: 303-43-5)
- CHOLESTERYL OLEYL CARBONATE (CAS RN: 17110-51-9)
- 2-(CHOLESTERYLOXY)ETHANOL
- CHOLESTERYL PALMITATE (CAS RN: 601-34-3)
- CHOLESTERYL PALMITELAIDATE (CAS RN: 102679-72-1)
- CHOLESTERYL PALMITOLEATE (CAS RN: 16711-66-3)
- CHOLESTERYL PELARGONATE (CAS RN: 1182-66-7)
- CHOLESTERYL PHENYLACETATE(CAS RN: 33998-26-4)
- CHOLESTERYL-P-PHENYL BENZOATE
- CHOLESTERYL PHOSPHORYL CHOLINE (CAS RN: 65956-64-1)
- CHOLESTERYL POLYETHYLENE GLYCOLS
- CHOLESTERYL PROPIONATE (CAS RN: 633-31-8)
- CHOLESTERYL N-PROPYL CARBONATE
- CHOLESTERYL PROPYL ETHER
- CHOLESTERYL 1-PYRENECARBOXYLATE (CAS RN: 253186-38-8)
- CHOLESTERYL (PYREN-1-YL)HEXANOATE (CAS RN: 96886-70-3)
- CHOLESTERYL STEARATE (CAS RN: 35602-69-8)
- CHOLESTERYL-P-TOSYLATE
- CHOLESTERYL N-(TRIMETHYLAMMONIOETHYL)CARBAMATE CHLORIDE (CAS RN: 188022-80-2)
- CHOLESTERYL TRICHLOROACETATE
- CHOLESTERYL UNDECANOATE (CAS RN: 30948-01-7)
- CHOLESTERYL VALERATE (CAS RN: 7726-03-6)
- CHOLESTERYL-P-NONYLOXYBENZOATE
- DICHOLESTERYL CARBONATE (CAS RN: 29331-39-3)
- DICHOLESTERYL SEBACATE
- DICHOLESTERYL SULFITE
- 7-KETOCHOLESTERYL ACETATE
- 6-NITROCHOLESTERYL BENZOATE
- PHENESTERIN (CAS RN: 3546-10-9)
- SODIUM CHOLESTERYL SULFATE
- THIOCHOLESTEROL (CAS RN: 1249-81-6)
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